Ligo Biosciences

What is Ligo Biosciences?

Ligo Biosciences leverages advanced generative diffusion models and deep learning to design new-to-nature enzymes that enable efficient biocatalysis across the $6 trillion chemical industry. By training on vast spatial and evolutionary data, Ligo’s AI can create enzymes with superior stability, catalytic activity, and intellectual property, surpassing traditional enzyme engineering methods that rely on modifying existing enzymes. Their technology accelerates enzyme design from years to days, targeting applications in pharmaceuticals, agriculture, carbon capture, and mining, making chemical production cheaper and more environmentally sustainable.

Key Features

• Generative Diffusion Enzyme Models

  Uses spatially aware AI models to design entirely new enzymes based on reaction transition states, enabling novel catalytic functions.

• Rapid Enzyme Design Cycle

  Reduces enzyme optimization timelines from years to days through AI-driven modeling and validation workflows.

• Enhanced Enzyme Performance

  Produces enzymes with higher precision, stability, and catalytic activity tailored for industrial applications.

• Broad Industrial Applications

  Applicable in pharmaceuticals, agriculture, chemical manufacturing, carbon capture, and mineral extraction.

• Data-Driven Innovation

  Leverages extensive structural and evolutionary datasets, including partnerships to expand sequence diversity and protein foundry capabilities.

Use Cases

• Pharmaceutical Manufacturing : Designs enzymatic cascades to produce active pharmaceutical ingredients more cost-effectively and sustainably.
• Agricultural Enzyme Optimization : Redesigns enzymes like phytase to improve animal feed efficiency and crop protection rapidly.
• Sustainable Chemical Production : Creates enzymes that catalyze chemical reactions under mild conditions, reducing energy use and greenhouse gas emissions.
• Carbon Capture Enhancement : Engineers enzymes to overcome natural limitations in biological carbon removal systems.
• Mineral Extraction : Develops enzymes capable of liberating valuable minerals such as lithium from ores inaccessible by traditional mining.

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