PipeBio

What is PipeBio?

PipeBio is a no-code, cloud-based platform designed for scientists and bioinformaticians to accelerate the discovery and engineering of antibodies, TCRs, and peptides. It provides a comprehensive suite of tools for large-scale sequence analysis, annotation, clustering, and visualization, supporting efficient data management and streamlined workflows. The platform integrates seamlessly with ELN, LIMS, and internal tools, and offers a robust REST API for building automated pipelines. PipeBio enables users to analyze NGS and Sanger data, identify candidate sequences, assess developability, and optimize antibody engineering, all within a secure and collaborative environment.

Key Features

• Comprehensive Sequence Analysis

  Analyze BCR, TCR, VHH, scFv, and peptide sequences with tools for annotation, clustering, and mutation detection.

• Automated Workflow Configuration

  Set up end-to-end workflows and standard operating procedures for antibody and peptide discovery, with integration to ELN and LIMS systems.

• Centralized Data Management

  Store sequences and associated metadata in a central database, enabling comparison across experiments and public datasets.

• Interactive Visualization Tools

  Visualize sequence clusters, amino acid frequencies, phylogenetic relationships, and enrichment analysis with interactive charts.

• REST API Integration

  Programmatically upload, download, and manage data, and build automated analysis pipelines through a robust API.

• Antibody Engineering Tools

  Edit sequences, optimize codons for synthesis, assess protein properties, and analyze developability and structural liabilities.

Use Cases

• Antibody Discovery and Screening : Accelerate identification of candidate antibodies from large-scale NGS and hybridoma datasets.
• Therapeutic Engineering : Optimize antibody and peptide sequences for developability and manufacturability.
• Bioinformatics Workflow Automation : Automate routine sequence analysis tasks and integrate with broader R&D data ecosystems.
• Data Visualization and Reporting : Generate interactive visualizations and reports for sequence diversity, clonal expansion, and enrichment analysis.
• Collaborative Research : Enable seamless data sharing and collaboration across research teams and organizations.

FAQs